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Sequence-dependent base pair stepping dynamics in XPD helicase unwinding

Helicases couple the chemical energy of ATP hydrolysis to directional translocation along nucleic acids and transient duplex separation. Understanding helicase mechanism requires that the basic physicochemical process of base pair separation be understood. This necessitates monitoring helicase activ...

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Autori principali: Qi, Zhi, Pugh, Robert A, Spies, Maria, Chemla, Yann R
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668415/
https://ncbi.nlm.nih.gov/pubmed/23741615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00334
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