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Asymmetric base-pair opening drives helicase unwinding dynamics
The opening of a Watson–Crick double helix is required for crucial cellular processes, including replication, repair, and transcription. It has long been assumed that RNA or DNA base pairs are broken by the concerted symmetric movement of complementary nucleobases. By analyzing thousands of base-pai...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842596/ https://ncbi.nlm.nih.gov/pubmed/31628254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901086116 |
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