Asymmetric base-pair opening drives helicase unwinding dynamics

The opening of a Watson–Crick double helix is required for crucial cellular processes, including replication, repair, and transcription. It has long been assumed that RNA or DNA base pairs are broken by the concerted symmetric movement of complementary nucleobases. By analyzing thousands of base-pai...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Colizzi, Francesco, Perez-Gonzalez, Cibran, Fritzen, Remi, Levy, Yaakov, White, Malcolm F., Penedo, J. Carlos, Bussi, Giovanni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
Physical Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842596/
https://ncbi.nlm.nih.gov/pubmed/31628254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901086116
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