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Targeted chromosomal deletions and inversions in zebrafish

Zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) provide powerful platforms for genome editing in plants and animals. Typically, a single nuclease is sufficient to disrupt the function of protein-coding genes through the introduction of microdeletions or inse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Ankit, Hall, Victoria L., Kok, Fatma O., Shin, Masahiro, McNulty, Joseph C., Lawson, Nathan D., Wolfe, Scot A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668355/
https://ncbi.nlm.nih.gov/pubmed/23478401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.154070.112
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