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A Review of Targeted Therapies Evaluated by the Pediatric Preclinical Testing Program for Osteosarcoma

Osteosarcoma, the most common malignant bone tumor of childhood, is a high-grade primary bone sarcoma that occurs mostly in adolescence. Standard treatment consists of surgery in combination with multi-agent chemotherapy regimens. The development and approval of imatinib for Philadelphia chromosome-...

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Bibliografiske detaljer
Main Authors: Sampson, Valerie B., Gorlick, Richard, Kamara, Davida, Anders Kolb, E.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668267/
https://ncbi.nlm.nih.gov/pubmed/23755370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00132
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