In vivo and in silico analysis of PCNA ubiquitylation in the activation of the Post Replication Repair pathway in S. cerevisiae

BACKGROUND: The genome of living organisms is constantly exposed to several damaging agents that induce different types of DNA lesions, leading to cellular malfunctioning and onset of many diseases. To maintain genome stability, cells developed various repair and tolerance systems to counteract the...

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Autors principals: Amara, Flavio, Colombo, Riccardo, Cazzaniga, Paolo, Pescini, Dario, Csikász-Nagy, Attila, Falconi, Marco Muzi, Besozzi, Daniela, Plevani, Paolo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668150/
https://ncbi.nlm.nih.gov/pubmed/23514624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-24
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