Reversal of PCNA Ubiquitylation by Ubp10 in Saccharomyces cerevisiae

Regulation of PCNA ubiquitylation plays a key role in the tolerance to DNA damage in eukaryotes. Although the evolutionary conserved mechanism of PCNA ubiquitylation is well understood, the deubiquitylation of ubPCNA remains poorly characterized. Here, we show that the histone H2B(K123) ubiquitin pr...

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Main Authors: Gallego-Sánchez, Alfonso, Andrés, Sonia, Conde, Francisco, San-Segundo, Pedro A., Bueno, Avelino
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400564/
https://ncbi.nlm.nih.gov/pubmed/22829782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002826
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