Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs). Incorporating eQTL information hence has potential to increase power of genome-wide association studies (GWAS). In this paper, we...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Lin, Kabesch, Michael, Bouzigon, Emmanuelle, Demenais, Florence, Farrall, Martin, Moffatt, Miriam F., Lin, Xihong, Liang, Liming
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2013
Ämnen:
Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668139/
https://ncbi.nlm.nih.gov/pubmed/23755072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00103
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