Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs). Incorporating eQTL information hence has potential to increase power of genome-wide association studies (GWAS). In this paper, we...

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Detalhes bibliográficos
Main Authors: Li, Lin, Kabesch, Michael, Bouzigon, Emmanuelle, Demenais, Florence, Farrall, Martin, Moffatt, Miriam F., Lin, Xihong, Liang, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668139/
https://ncbi.nlm.nih.gov/pubmed/23755072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00103
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