Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs). Incorporating eQTL information hence has potential to increase power of genome-wide association studies (GWAS). In this paper, we...

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Главные авторы: Li, Lin, Kabesch, Michael, Bouzigon, Emmanuelle, Demenais, Florence, Farrall, Martin, Moffatt, Miriam F., Lin, Xihong, Liang, Liming
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2013
Предметы:
Genetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668139/
https://ncbi.nlm.nih.gov/pubmed/23755072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00103
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