Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma

Increasing evidence suggests that single nucleotide polymorphisms (SNPs) associated with complex traits are more likely to be expression quantitative trait loci (eQTLs). Incorporating eQTL information hence has potential to increase power of genome-wide association studies (GWAS). In this paper, we...

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Bibliographische Detailangaben
Hauptverfasser: Li, Lin, Kabesch, Michael, Bouzigon, Emmanuelle, Demenais, Florence, Farrall, Martin, Moffatt, Miriam F., Lin, Xihong, Liang, Liming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668139/
https://ncbi.nlm.nih.gov/pubmed/23755072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00103
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