A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

Classical immunohistochemical studies in the Alzheimer disease (AD) brain reveal prominent glial reactions, but whether this pathological feature is due primarily to cell proliferation or to a phenotypic change of existing resting cells remains controversial. We performed double-fluorescence immunoh...

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Bibliographische Detailangaben
Hauptverfasser: Serrano-Pozo, Alberto, Gómez-Isla, Teresa, Growdon, John H., Frosch, Matthew P., Hyman, Bradley T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2013
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668030/
https://ncbi.nlm.nih.gov/pubmed/23602650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.031
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