A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

Classical immunohistochemical studies in the Alzheimer disease (AD) brain reveal prominent glial reactions, but whether this pathological feature is due primarily to cell proliferation or to a phenotypic change of existing resting cells remains controversial. We performed double-fluorescence immunoh...

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Hlavní autoři: Serrano-Pozo, Alberto, Gómez-Isla, Teresa, Growdon, John H., Frosch, Matthew P., Hyman, Bradley T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2013
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668030/
https://ncbi.nlm.nih.gov/pubmed/23602650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.031
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