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A “vicious cycle” of NK-cell immune evasion in acute myeloid leukemia mediated by RANKL?

Receptor activator of NFκB ligand (RANKL) is mainly known for its role in bone metabolism, constituting a target for therapeutic interventions. Increasing evidence suggests that RANKL is also involved in oncogenesis and tumor progression, including a prominent role in host-tumor interaction. Our dat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schmiedel, Benjamin Joachim, Grosse-Hovest, Ludger, Salih, Helmut Rainer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667891/
https://ncbi.nlm.nih.gov/pubmed/23762785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.23850
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