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Inhibition of TDP-43 Aggregation by Nucleic Acid Binding
The aggregation of TAR DNA-binding protein (TDP-43) has been shown as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) since 2006. While evidence has suggested that mutation or truncation in TDP-43 influences its aggregation process, nevertheless, the co...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667863/ https://ncbi.nlm.nih.gov/pubmed/23737961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064002 |
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