Transient expression of human adenosine deaminase cDNAs: identification of a nonfunctional clone resulting from a single amino acid substitution.

Human adenosine deaminase (ADA) is an important purine catabolic enzyme which irreversibly deaminates adenosine and deoxyadenosine. Severe genetic deficiency of ADA leads to an immunological deficiency state in which T-lymphoid cells are selectively destroyed by the accumulation of toxic levels of d...

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Bibliografske podrobnosti

izdano v:	Mol Cell Biol
Principais autores:	Orkin, S H, Goff, S C, Kelley, W N, Daddona, P E
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1985
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3838797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.4.762-767.1985
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