Transient expression of human adenosine deaminase cDNAs: identification of a nonfunctional clone resulting from a single amino acid substitution.

Human adenosine deaminase (ADA) is an important purine catabolic enzyme which irreversibly deaminates adenosine and deoxyadenosine. Severe genetic deficiency of ADA leads to an immunological deficiency state in which T-lymphoid cells are selectively destroyed by the accumulation of toxic levels of d...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Orkin, S H, Goff, S C, Kelley, W N, Daddona, P E
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3838797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.4.762-767.1985
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