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Rhes Deletion Is Neuroprotective in the 3-Nitropropionic Acid Model of Huntington's Disease
Although the mutated protein causing Huntington's disease (HD) is expressed throughout the body, the major pathology of HD is localized to the striatum of the brain. We previously reported that the striatal-enriched protein Rhes binds the mutated huntingtin protein and enhances its cytotoxicity...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667505/ https://ncbi.nlm.nih.gov/pubmed/23447628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3730-12.2013 |
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