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On Estimation of Allele Frequencies via Next-Generation DNA Resequencing with Barcoding

Next Generation Sequencing (NGS) has revolutionized biomedical research in recent years. It is now commonly used to identify rare variants through re-sequencing individual genomes. Due to the cost of NGS, researchers have considered pooling samples as a cost-effective alternative to individual seque...

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Detalhes bibliográficos
Main Authors: Lee, Joon Sang, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666873/
https://ncbi.nlm.nih.gov/pubmed/23730349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12561-013-9084-y
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