Chloride binding site of neurotransmitter sodium symporters

Neurotransmitter:sodium symporters (NSSs) play a critical role in signaling by reuptake of neurotransmitters. Eukaryotic NSSs are chloride-dependent, whereas prokaryotic NSS homologs like LeuT are chloride-independent but contain an acidic residue (Glu290 in LeuT) at a site where eukaryotic NSSs hav...

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Autores principales: Kantcheva, Adriana K., Quick, Matthias, Shi, Lei, Winther, Anne-Marie Lund, Stolzenberg, Sebastian, Weinstein, Harel, Javitch, Jonathan A., Nissen, Poul
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666746/
https://ncbi.nlm.nih.gov/pubmed/23641004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221279110
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