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X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

Arylsulfatases require a maturating enzyme to perform a co- or posttranslational modification to form a catalytically essential formylglycine (FGly) residue. In organisms that live aerobically, molecular oxygen is used enzymatically to oxidize cysteine to FGly. Under anaerobic conditions, S-adenosyl...

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Hlavní autoři: Goldman, Peter J., Grove, Tyler L., Sites, Lauren A., McLaughlin, Martin I., Booker, Squire J., Drennan, Catherine L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666706/
https://ncbi.nlm.nih.gov/pubmed/23650368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302417110
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