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Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties

Despite the increasing prevalence of heart failure with preserved left ventricular function, there are no specific treatments, partially because the mechanism of impaired relaxation is incompletely understood. Evidence indicates that cardiac relaxation may depend on nitric oxide (NO), generated by N...

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Bibliographic Details
Main Authors: Jeong, Euy-Myoung, Monasky, Michelle M., Gu, Lianzhi, Taglieri, Domenico M., Patel, Bindiya G., Liu, Hong, Wang, Qiongying, Greener, Ian, Dudley, Samuel C., Solaro, R. John
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666585/
https://ncbi.nlm.nih.gov/pubmed/23247392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.12.003
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