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Tetrahydrobiopterin improves diastolic dysfunction by reversing changes in myofilament properties

Despite the increasing prevalence of heart failure with preserved left ventricular function, there are no specific treatments, partially because the mechanism of impaired relaxation is incompletely understood. Evidence indicates that cardiac relaxation may depend on nitric oxide (NO), generated by N...

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Main Authors: Jeong, Euy-Myoung, Monasky, Michelle M., Gu, Lianzhi, Taglieri, Domenico M., Patel, Bindiya G., Liu, Hong, Wang, Qiongying, Greener, Ian, Dudley, Samuel C., Solaro, R. John
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666585/
https://ncbi.nlm.nih.gov/pubmed/23247392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.12.003
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