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Thiophene-Core Estrogen Receptor Ligands Having Superagonist Activity
To probe the importance of the heterocyclic core of estrogen receptor (ER) ligands, we prepared a series of thiophene-core ligands by Suzuki cross-coupling of aryl boronic acids with bromo-thiophenes, and we assessed their receptor binding and cell biological activities. The disposition of the pheno...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666579/ https://ncbi.nlm.nih.gov/pubmed/23586645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400157e |
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