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Impact of macromolecular crowding on DNA replication

Enzymatic activities in vivo occur in a crowded environment composed of many macromolecules. This environment influences DNA replication by increasing the concentration of the constituents, desolvation, decreasing the degrees of freedom for diffusion and hopping of proteins onto DNA, and enhancing b...

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Detalhes bibliográficos
Main Authors: Akabayov, Barak, Akabayov, Sabine R., Lee, Seung–Joo, Wagner, Gerhard, Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666333/
https://ncbi.nlm.nih.gov/pubmed/23511479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2620
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