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ACUTE ELEVATIONS OF BRAIN KYNURENIC ACID IMPAIR COGNITIVE FLEXIBILITY: NORMALIZATION BY THE ALPHA 7 POSITIVE MODULATOR GALANTAMINE
RATIONALE: Cognitive deficits represent a core symptom cluster in schizophrenia (SZ) that is predictive of functional outcome, but not effectively treated by current antipsychotics. Thus, there is a need for the development of validated animal models for testing potential cognition-enhancing drugs....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3666324/ https://ncbi.nlm.nih.gov/pubmed/22038535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2539-2 |
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