ACUTE ELEVATIONS OF BRAIN KYNURENIC ACID IMPAIR COGNITIVE FLEXIBILITY: NORMALIZATION BY THE ALPHA 7 POSITIVE MODULATOR GALANTAMINE

RATIONALE: Cognitive deficits represent a core symptom cluster in schizophrenia (SZ) that is predictive of functional outcome, but not effectively treated by current antipsychotics. Thus, there is a need for the development of validated animal models for testing potential cognition-enhancing drugs....

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Hlavní autoři: Alexander, Kathleen S., Wu, Hui-Qiu, Schwarcz, Robert, Bruno, John P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666324/
https://ncbi.nlm.nih.gov/pubmed/22038535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2539-2
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