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Intracellular Zn(2+) accumulation enhances suppression of synaptic activity following spreading depolarization

Spreading depolarization (SD) is a feed-forward wave that propagates slowly throughout brain tissue and recovery from SD involves substantial metabolic demand. Presynaptic Zn(2+) release and intracellular accumulation occurs with SD, and elevated intracellular Zn(2+) ([Zn(2+)](i)) can impair cellula...

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Detalhes bibliográficos
Main Authors: Carter, Russell E., Seidel, Jessica L., Lindquist, Britta E., Sheline, Christian T., Shuttleworth, C. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666321/
https://ncbi.nlm.nih.gov/pubmed/23495967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12237
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