Spreading depolarization-induced adenosine accumulation reflects metabolic status in vitro and in vivo

Spreading depolarization (SD), a pathologic feature of migraine, stroke and traumatic brain injury, is a propagating depolarization of neurons and glia causing profound metabolic demand. Adenosine, the low-energy metabolite of ATP, has been shown to be elevated after SD in brain slices and under con...

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Bibliographic Details
Published in:J Cereb Blood Flow Metab
Main Authors: Lindquist, Britta E, Shuttleworth, C William
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269755/
https://ncbi.nlm.nih.gov/pubmed/25160669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.146
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