Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury

Connexin-43 (Cx43), a predominant cardiac connexin, forms gap junctions (GJs) that facilitate electrical cell–cell coupling and unapposed/nonjunctional hemichannels that provide a pathway for the exchange of ions and metabolites between cytoplasm and extracellular milieu. Uncontrolled opening of hem...

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Bibliografische gegevens
Hoofdauteurs: Wang, Nan, De Vuyst, Elke, Ponsaerts, Raf, Boengler, Kerstin, Palacios-Prado, Nicolás, Wauman, Joris, Lai, Charles P., De Bock, Marijke, Decrock, Elke, Bol, Mélissa, Vinken, Mathieu, Rogiers, Vera, Tavernier, Jan, Evans, W. Howard, Naus, Christian C., Bukauskas, Feliksas F., Sipido, Karin R., Heusch, Gerd, Schulz, Rainer, Bultynck, Geert, Leybaert, Luc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666173/
https://ncbi.nlm.nih.gov/pubmed/23184389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0309-x
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