Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury

Connexin-43 (Cx43), a predominant cardiac connexin, forms gap junctions (GJs) that facilitate electrical cell–cell coupling and unapposed/nonjunctional hemichannels that provide a pathway for the exchange of ions and metabolites between cytoplasm and extracellular milieu. Uncontrolled opening of hem...

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Hauptverfasser: Wang, Nan, De Vuyst, Elke, Ponsaerts, Raf, Boengler, Kerstin, Palacios-Prado, Nicolás, Wauman, Joris, Lai, Charles P., De Bock, Marijke, Decrock, Elke, Bol, Mélissa, Vinken, Mathieu, Rogiers, Vera, Tavernier, Jan, Evans, W. Howard, Naus, Christian C., Bukauskas, Feliksas F., Sipido, Karin R., Heusch, Gerd, Schulz, Rainer, Bultynck, Geert, Leybaert, Luc
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666173/
https://ncbi.nlm.nih.gov/pubmed/23184389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0309-x
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