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Intracellular Cleavage of the Cx43 C-Terminal Domain by Matrix-Metalloproteases: A Novel Contributor to Inflammation?

The coordination of tissue function is mediated by gap junctions (GJs) that enable direct cell-cell transfer of metabolic and electric signals. GJs are formed by connexin (Cx) proteins of which Cx43 is most widespread in the human body. Beyond its role in direct intercellular communication, Cx43 als...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: De Bock, Marijke, Wang, Nan, Decrock, Elke, Bultynck, Geert, Leybaert, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573893/
https://ncbi.nlm.nih.gov/pubmed/26424967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/257471
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