Spectraplakins Promote Microtubule-Mediated Axonal Growth by Functioning As Structural Microtubule-Associated Proteins and EB1-Dependent +TIPs (Tip Interacting Proteins)

The correct outgrowth of axons is essential for the development and regeneration of nervous systems. Axon growth is primarily driven by microtubules. Key regulators of microtubules in this context are the spectraplakins, a family of evolutionarily conserved actin-microtubule linkers. Loss of functio...

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Auteurs principaux: Alves-Silva, Juliana, Sánchez-Soriano, Natalia, Beaven, Robin, Klein, Melanie, Parkin, Jill, Millard, Thomas H., Bellen, Hugo J., Venken, Koen J. T., Ballestrem, Christoph, Kammerer, Richard A., Prokop, Andreas
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666083/
https://ncbi.nlm.nih.gov/pubmed/22764224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0416-12.2012
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