Spectraplakins Promote Microtubule-Mediated Axonal Growth by Functioning As Structural Microtubule-Associated Proteins and EB1-Dependent +TIPs (Tip Interacting Proteins)

The correct outgrowth of axons is essential for the development and regeneration of nervous systems. Axon growth is primarily driven by microtubules. Key regulators of microtubules in this context are the spectraplakins, a family of evolutionarily conserved actin-microtubule linkers. Loss of functio...

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Main Authors: Alves-Silva, Juliana, Sánchez-Soriano, Natalia, Beaven, Robin, Klein, Melanie, Parkin, Jill, Millard, Thomas H., Bellen, Hugo J., Venken, Koen J. T., Ballestrem, Christoph, Kammerer, Richard A., Prokop, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666083/
https://ncbi.nlm.nih.gov/pubmed/22764224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0416-12.2012
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