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Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show that the plus-end scaffold Eb1, the polymerase XMAP...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Hahn, Ines, Voelzmann, Andre, Parkin, Jill, Fülle, Judith B., Slater, Paula G., Lowery, Laura Anne, Sanchez-Soriano, Natalia, Prokop, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284659/
https://ncbi.nlm.nih.gov/pubmed/34228717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009647
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