Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show that the plus-end scaffold Eb1, the polymerase XMAP...

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Publicat a:PLoS Genet
Autors principals: Hahn, Ines, Voelzmann, Andre, Parkin, Jill, Fülle, Judith B., Slater, Paula G., Lowery, Laura Anne, Sanchez-Soriano, Natalia, Prokop, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284659/
https://ncbi.nlm.nih.gov/pubmed/34228717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009647
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