Dimerization and Ubiquitin Mediated Recruitment of A20, a Complex Deubiquitinating Enzyme

A20 is an anti-inflammatory protein linked to multiple human autoimmune diseases and lymphomas. A20 possesses a deubiquitinating motif and a zinc finger, ZF4, that binds ubiquitin and supports its E3 ubiquitin ligase activity. To understand how these activities mediate A20’s physiological functions,...

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Hauptverfasser: Lu, Timothy T., Onizawa, Michio, Hammer, Gianna, Turer, Emre E., Yin, Qian, Damko, Ermelinda, Agelides, Alex, Shifrin, Nataliya, Advincula, Rommel, Barrera, Julio, Malynn, Barbara A., Wu, Hao, Ma, Averil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665706/
https://ncbi.nlm.nih.gov/pubmed/23602765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.03.008
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