The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression

The CtIP protein facilitates homology-directed repair (HDR) of double-strand DNA breaks (DSBs) by initiating DNA resection, a process in which DSB ends are converted into 3′-ssDNA overhangs. The BRCA1 tumor suppressor, which interacts with CtIP in a phospho-dependent manner, has also been implicated...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Reczek, Colleen R., Szabolcs, Matthias, Stark, Jeremy M., Ludwig, Thomas, Baer, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2013
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664708/
https://ncbi.nlm.nih.gov/pubmed/23712259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201302145
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller