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Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity

The Rod-derived Cone Viability Factors, RdCVF and RdCVF2, have potential therapeutical interests for the treatment of inherited photoreceptor degenerations. In the mouse lacking Nxnl2, the gene encoding RdCVF2, the progressive decline of the visual performance of the cones in parallel with their deg...

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Detalhes bibliográficos
Main Authors: Jaillard, Céline, Mouret, Aurélie, Niepon, Marie-Laure, Clérin, Emmanuelle, Yang, Ying, Lee-Rivera, Irene, Aït-Ali, Najate, Millet-Puel, Géraldine, Cronin, Thérèse, Sedmak, Tina, Raffelsberger, Wolfgang, Kinzel, Bernd, Trembleau, Alain, Poch, Olivier, Bennett, Jean, Wolfrum, Uwe, Lledo, Pierre-Marie, Sahel, José-Alain, Léveillard, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664437/
https://ncbi.nlm.nih.gov/pubmed/22343139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds050
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