A Splice Variant in SLC16A8 Gene Leads to Lactate Transport Deficit in Human iPS Cell-Derived Retinal Pigment Epithelial Cells

Age-related macular degeneration (AMD) is a blinding disease for which most of the patients remain untreatable. Since the disease affects the macula at the center of the retina, a structure specific to the primate lineage, rodent models to study the pathophysiology of AMD and to develop therapies ar...

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Udgivet i:Cells
Main Authors: Klipfel, Laurence, Cordonnier, Marie, Thiébault, Léa, Clérin, Emmanuelle, Blond, Frédéric, Millet-Puel, Géraldine, Mohand-Saïd, Saddek, Goureau, Olivier, Sahel, José-Alain, Nandrot, Emeline F., Léveillard, Thierry
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831140/
https://ncbi.nlm.nih.gov/pubmed/33477551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010179
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