Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation

Inherited retinal degenerations are blinding diseases characterized by the loss of photoreceptors. Their extreme genetic heterogeneity complicates treatment by gene therapy. This has motivated broader strategies for transplantation of healthy retinal pigmented epithelium to protect photoreceptors in...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Kole, Christo, Klipfel, Laurence, Yang, Ying, Ferracane, Vanessa, Blond, Frederic, Reichman, Sacha, Millet-Puel, Géraldine, Clérin, Emmanuelle, Aït-Ali, Najate, Pagan, Delphine, Camara, Hawa, Delyfer, Marie-Noëlle, Nandrot, Emeline F., Sahel, Jose-Alain, Goureau, Olivier, Léveillard, Thierry
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762984/
https://ncbi.nlm.nih.gov/pubmed/28988713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.09.007
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