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Structure-Activity Relationship Exploration of Kv1.3 Blockers Based on Diphenoxylate
[Image: see text] Diphenoxylate, a well-known opioid agonist and anti-diarrhoeal agent, was recently found to block Kv1.3 potassium channels, which have been proposed as potential therapeutic targets for a range of autoimmune diseases. The molecular basis for this Kv1.3 blockade was assessed by the...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664202/ https://ncbi.nlm.nih.gov/pubmed/23084278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.09.080 |
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