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4-Phenoxybutoxy-substituted Heterocycles - a Structure-Activity Relationship Study of Blockers of the Lymphocyte Potassium Channel Kv1.3
The voltage-gated potassium channel Kv1.3 constitutes an attractive pharmacological target for the treatment of effector memory T cell-mediated autoimmune diseases such as multiple sclerosis and psoriasis. Using 5-methoxypsoralen (5-MOP, 1), a compound isolated from Ruta graveolens, as a template we...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662044/ https://ncbi.nlm.nih.gov/pubmed/19056148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.10.033 |
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