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Alzheimer’s disease: Which type of amyloid-preventing drug agents to employ?
The current paradigm in the amyloid hypothesis brands small β-amyloid (Aβ) oligomers as the toxic species in Alzheimer’s disease (AD). These oligomers are fibril-like; contain β-sheet structure, and present exposed hydrophobic surface. Oligomers with this motif are capable of penetrating the cell me...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663909/ https://ncbi.nlm.nih.gov/pubmed/23450150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cp00017f |
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