Post-Transcriptional Dysregulation by miRNAs Is Implicated in the Pathogenesis of Gastrointestinal Stromal Tumor [GIST]

In contrast to adult mutant gastrointestinal stromal tumors [GISTs], pediatric/wild-type GISTs remain poorly understood overall, given their lack of oncogenic activating tyrosine kinase mutations. These GISTs, with a predilection for gastric origin in female patients, show limited response to therap...

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Hauptverfasser: Kelly, Lorna, Bryan, Kenneth, Kim, Su Young, Janeway, Katherine A., Killian, J. Keith, Schildhaus, Hans-Ulrich, Miettinen, Markku, Helman, Lee, Meltzer, Paul S., van de Rijn, Matt, Debiec-Rychter, Maria, O’Sullivan, Maureen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663836/
https://ncbi.nlm.nih.gov/pubmed/23717541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064102
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