Structural Insights into the Chaperone Activity of the 40-kDa Heat Shock Protein DnaJ: BINDING AND REMODELING OF A NATIVE SUBSTRATE

Hsp40 chaperones bind and transfer substrate proteins to Hsp70s and regulate their ATPase activity. The interaction of Hsp40s with native proteins modifies their structure and function. A good model for this function is DnaJ, the bacterial Hsp40 that interacts with RepE, the repressor/activator of p...

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Bibliographic Details
Main Authors: Cuéllar, Jorge, Perales-Calvo, Judit, Muga, Arturo, Valpuesta, José María, Moro, Fernando
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663527/
https://ncbi.nlm.nih.gov/pubmed/23580641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430595
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