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Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface

The heat shock protein 70 kDa (Hsp70)/DnaJ/nucleotide exchange factor system assists in intracellular protein (re)folding. Using solution NMR, we obtained a three-dimensional structure for a 75-kDa Hsp70–DnaJ complex in the ADP state, loaded with substrate peptide. We establish that the J domain (re...

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Hlavní autoři: Ahmad, Atta, Bhattacharya, Akash, McDonald, Ramsay A., Cordes, Melissa, Ellington, Benjamin, Bertelsen, Eric B., Zuiderweg, Erik R. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223468/
https://ncbi.nlm.nih.gov/pubmed/22065753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111220108
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