Mutations in the DnaK chaperone affecting interaction with the DnaJ cochaperone

Hsp70 chaperones assist protein folding by ATP-controlled cycles of substrate binding and release. ATP hydrolysis is the rate-limiting step of the ATPase cycle that causes locking in of substrates into the substrate-binding cavity of Hsp70. This key step is strongly stimulated by DnaJ cochaperones....

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gässler, Claudia S., Buchberger, Alexander, Laufen, Thomas, Mayer, Matthias P., Schröder, Hartwig, Valencia, Alfonso, Bukau, Bernd
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28025/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9860951/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15229
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