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Dbf4 and Cdc7 Proteins Promote DNA Replication through Interactions with Distinct Mcm2–7 Protein Subunits

The essential cell cycle target of the Dbf4/Cdc7 kinase (DDK) is the Mcm2–7 helicase complex. Although Mcm4 has been identified as the critical DDK phosphorylation target for DNA replication, it is not well understood which of the six Mcm2–7 subunits actually mediate(s) docking of this kinase comple...

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Detalles Bibliográficos
Main Authors: Ramer, Matthew D., Suman, Evelyin S., Richter, Hagen, Stanger, Karen, Spranger, Martina, Bieberstein, Nicole, Duncker, Bernard P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663514/
https://ncbi.nlm.nih.gov/pubmed/23549044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.392910
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