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A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

Using a reconstituted DNA replication assay from yeast, we demonstrate that two kinase complexes are essential for the promotion of replication in vitro. An active Clb/Cdc28 kinase complex, or its vertebrate equivalent, is required in trans to stimulate initiation in G(1)-phase nuclei, whereas the D...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pasero, Philippe, Duncker, Bernard P., Schwob, Etienne, Gasser, Susan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC316966/
https://ncbi.nlm.nih.gov/pubmed/10465792
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