The Spontaneously Adhesive Leukocyte Function-associated Antigen-1 (LFA-1) Integrin in Effector T Cells Mediates Rapid Actin- and Calmodulin-dependent Adhesion Strengthening to Ligand under Shear Flow

Integrins in effector T cells are highly expressed and important for trafficking of these cells and for their effector functions. However, how integrins are regulated in effector T cells remains poorly characterized. Here, we have investigated effector T cell leukocyte function-associated antigen-1...

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Detalhes bibliográficos
Main Authors: Lek, Hwee San, Morrison, Vicky L., Conneely, Michael, Campbell, Paul A., McGloin, David, Kliche, Stefanie, Watts, Colin, Prescott, Alan, Fagerholm, Susanna C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663495/
https://ncbi.nlm.nih.gov/pubmed/23585567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430918
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